By harnessing complex data, Syapse is changing the way we fight cancer, making meaningful improvements in the lives of patients at some of the nation’s largest healthcare institutions.

Founded 2008
51-200 employees
  • Health Care Technology & Nursing
  • Biotechnology & Chemical Products
  • Headquarters address
    303 2nd St., San Francisco, CA
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    Why work here?

    You have so many choices of places to work in the software world. At Syapse, you will build software that quantifiably saves lives. Sure, you can build advertising networks, make tools for financial institutions, help retailers target buyers...the options are endless. But are you excited by any of these choices?

    As part of the Syapse team you'll be helping to cure cancer and deliver the right therapies to the right people at the right time with software for Precision Medicine.

    “The dawning era of precision medicine promises to transform health over the next several decades through significant advances that improve our understanding of the molecular nature of disease, our ability to more precisely treat, cure, and prevent disease in ever more precise ways.”
    - UCSF Chancellor Sam Hawgood

    Ask anyone here to describe why they choose to work at Syapse and the word “meaningful” comes up.

    Why do we do what we do?

    The people of Syapse are committed to work that makes a direct impact in people’s lives. It is hard to find anyone not affected by cancer. We are proud of our work and how it has helped to improve patients’ health.

    How do we do what we do?

    Syapse software helps healthcare providers use next-generation genomic and molecular data, in context with complex clinical data (medical history, treatment, outcomes, cost, etc.) spread across multiple systems, to make the best decisions regarding patient care.

    We have a team of experts including physicians, biologists, software engineers, and others at the top of their game building a complex, powerful system in a challenging and collaborative environment. Our team comes from top schools including Stanford, Cal, MIT, Georgetown, UC Davis, Yale, UCLA, USC, University of Illinois and from influential companies such as Google, Illumina, 23andMe, Genentech, NextGen, and Epic.

    What do we do?

    We have built a cloud-based SaaS solution to serve healthcare providers at the cutting edge of precision medicine. The service is based upon a data platform that combines semantic technologies, data integration, and a scalable, enterprise back end to provide a unique foundation for medical applications that use genomic and other molecular data. On top of this platform we develop a suite of single-page JavaScript applications, with innovative, semantic metadata-driven interfaces.


    We have 2 locations. Headquarters is in beautiful downtown San Francisco blocks from the ballpark. We also have an office in Wayne, PA (just outside Philadelphia). We are in the midst of a huge expansion where you will have the opportunity to shape the team and culture going forward. Medical, dental, vision, transit subsidies, flexible PTO, competitive pay and equity.

    Tech stack

    Python, Java, JavaScript, HTML5, CSS3, React, Redux, Semantic Web Stack (SPARQL, RDF, OWL)


    Compensation and retirement

    401k plan

    Health and wellness

    Insurance (Health)
    Insurance (Dental)
    Insurance (Vision)
    Insurance (Life)
    Insurance (Disability)

    Values and quality of life

    Catered meals
    Syapse - HQ All hands meeting
    Syapse - Collaborative environment
    Syapse - Adjustable desks, open enviroment